Hyper-tonic & Hypo-tonic

I have become very conscious of my cells’ relationship to water, and what causes them to hold or retain water, and what causes them to shed water.

For a while (after living in a moldy house), I had such dramatic issues with edema (swelling, water retention) that it was thought I had a deficiency of vitamin B6. I took zinc and B6 for a while, and it seemed to help somewhat. I was diagnosed with “pyroluria,” an alleged defect in heme synthesis, a condition with some similarities to porphyria.

But I kept searching for deeper answers. I don’t like to fix things with bandaids; I like to try to understand the root cause. It was by observing the effects of mold, of an accelerated rate of decay—could illness have to do with the speed of time?—that I became interested in physics and its potential relationship to human health.

This issue with water, this tensile issue of the rigidity of cells, of how much water they retain or do not retain, seems simple—but its effects writ large could be profound.

When I retain a lot of water (e.g. pre menstruation) the amount of tension in the cells is quite high. They feel hyper-tonic to me—bloated, swollen, larger than the baseline. When I am larger than the baseline, the internal tension is too high and there is no longer homeostasis (balance). I can feel that these hyper-tonic cells want to contract or collapse. When my cells are hyper-tonic (swollen), and I provide vitamin K1 serum, they condense immediately. I have felt this with breasts cysts (polycystic breasts) and with ovarian cysts (PCOS).

There is a mirror-image state that I call “hypo-tonic.” Dehydrated. When my cells are dehydrated, they want to expand. When I am dehydrated—smaller than baseline, the external tension is too high and there is no longer homeostasis (balance). I can feel that these hypo-tonic cells want to expand. When my cells are hypo-tonic (dehydrated), and I supply vitamin K2, they expand immediately. Lately (2022-2023) I do not tolerate vitamin K2 at all; it is as if I have reached some sort of expansion limit. K2 makes it feel as if my pineal gland is under water, is hyper-tonic (swollen), and I get dizzy and lose my sense of balance and proprioception.

In other words, what is my relationship to my environment? Am I less dense? Or more dense? When I am less dense, I want to condense. When I am more dense, I want to expand.

Hypo-tonic: If I am more dense (less watery) than my environment, it is as if I am too small—the “vacuum” is outside me. I want to expand, the fill the vacuum.

Hyper-tonic: If I am more diffuse (more watery) than my environment, it is as if I am too large—the “vacuum” is inside me. I want to condense, to fill the vacuum.

If I eat a diet very skewed toward glycine (the smallest amino acid), I start to feel too small—denser than my environment. I get the same feeling when I eat a lot of oxalate. Once I am denser than my environment, I have to fight the exploding force. I can do this with vitamin K1.

If I eat a diet very skewed toward tryptophan (the largest amino acid), I start to feel too large—more diffuse than my environment. I get the same feeling when I take a lot of vitamin B3 or niacin, which is a vasodilator. Once I am more diffuse than my environment, I have to fight the collapsing force.

Dealing with forces takes a lot of energy. If I am the same density as my environment, I do not have to deal with forces.

This feeling of “tension” between self and world is also known as a proton gradient.

The following is from Nick Lane in Quanta: “A Biochemist’s View of Life’s Origin Reframes Cancer and Aging.”

“About 10 years ago, the cancer community was amazed by the discovery that in some cancers, mutations can lead to parts of the Krebs cycle running backward. It came as quite a shock because the Krebs cycle is usually taught as only spinning forward to generate energy. But it turns out that while a cancer cell does need energy, what it really needs even more is carbon-based building blocks for growth. So the whole field of oncology began to see this reversal of the Krebs cycle as a kind of metabolic rewiring that helps cancer cells grow.”

I believe there is a metabolic “flip” that takes place—a switch from expansion to contraction, a pendulum that swings between the hyper-tonic and hypo-tonic state—that should be central to how we view our health and the cosmos itself.

If I am denser than baseline, I feel the exploding force. To oppose the exploding force, I can use vitamin K1. But K1, which I can use the thicken the blood, increase porphyrins, thicken the light, will reinforce the sensation that I am denser than baseline. This is a kind of loop.

If I am more diffuse than baseline, I feel the collapsing force. To oppose the collapsing force, I can use vitamin K2. But K2, which I can use to thin the blood, decrease porphyrins, thin the light, will reinforce the sensation that I am more diffuse than baseline. This, too, is a kind of loop.

“Evidence indicates that the hemostatic system is involved to some extent in the pathogenesis, morbidity, and prognosis of a wide variety of psychiatric disorders. The current review focuses on emerging data linking coagulation and some psychiatric disorders,” from Coagulation and Mental Disorders.

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