What if this is not a vacuum but a tightly controlled explosion. We don’t feel the exploding force or the collapsing force because—in the present—they are held in balance. But slip too far forward in time, and the centripetal (collapsing) force becomes too high (ALS?). Or, slip too far backward in time, and the centrifugal (exploding) force becomes too high (Parkinson’s?).
What if, with Autism, two things are wrong at once. My RBCs are too large, and the pressure in the system is too low. We don’t see the two dysfunctions because the system is consistent with itself. When my doctor told me: “Too many of your new RBCs are too large” it was only observable because there was a smaller set of RBCs in circulation. There was contrast—a background against which to observe their difference.
What if, with ME/CFS (Chronic Fatigue Syndrome), two things are wrong at once. My RBCs are too small, and the pressure in the system is too high. We don’t see the twin dysfunctions because the system is consistent with itself.
When the RBC is too small and the pressure in the system is too high, I am trapped. If I try to decrease the pressure, to “let go” of the RBC, I will lose the connection and lose consciousness. Since living in a moldy house, I have had a lot of issues with orthostatic intolerance.
Sustained, excessive vasodilation may be central to myalgic encephalomyelitis, (ME/CFS i.e. chronic fatigue syndrome). When I am too vasodilated, my nitric oxide or NO/ONOO cycle (and its downstream metabolic by-products) will be deranged. The idea of the nitric oxide cycle as central to ME/CFS was first championed by Martin L. Pall over twenty-five years ago. When I am too vasodilated—too “open”—I will perceive the sensory information of the world as too dense (sounds too loud, light too bright, smells too strong).
This vasodilation might be masked if the amount of fluid in my vascular system simultaneously increases. The combined effect is like that of a garden hose where, because the mouth is too open, I have to increase the force at the spout. ME/CFS may be a kind of contradiction. Because I am too vasodilated, I have hypotension. Because the force at the spout is too high, I have hypertension. Because I am keeping the volume and fluid pressure too high, I have to keep the hose open too wide. Because I am keeping the hose open too wide, I have to keep the volume and fluid pressure too high. When I am too dilated in time, it is as if the body—the image of my body—is the wrong size. The wrong scale.
